{"id":35,"date":"2018-02-07T12:26:39","date_gmt":"2018-02-07T17:26:39","guid":{"rendered":"https:\/\/pctk.jhu.edu\/?page_id=35"},"modified":"2018-02-09T14:35:56","modified_gmt":"2018-02-09T19:35:56","slug":"some-details-of-pctk","status":"publish","type":"page","link":"https:\/\/pctk.jhu.edu\/index.php\/some-details-of-pctk\/","title":{"rendered":"What PcTK can do"},"content":{"rendered":"

How it works<\/strong><\/p>\n

An x-ray photon interacts with photon counting detectors (PCDs) via various phenomena and generates an electron charge cloud or multiple clouds.<\/p>\n

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Fig. 1. Various interaction phenomena: (a) No interaction with PCD; (b-d) Photoelectric effects (b) with total absorption, (c) fluorescence x-ray emission and its escape from PCD, and (d) fluorescence x-ray emission and its re-absorption; and (e) Compton scattering and Rayleigh scattering. Compton scattering and Rayleigh scattering are not included in PcTK version 3.2. Figure is from Ref. 2.<\/figcaption><\/figure>\n

The clouds may be detected by two or more adjacent PCD pixels and the recorded energy may be lower than the original energy due to charge sharing (Fig. 1b), escape and reabsorption of a K-shell fluorescence x-ray (Figs. 1c\u20131d), etc. This is called double-counting or n<\/em>-tuple-counting. As a result, PCD data are spatially and energetically correlated. The Photon Counting Toolkit (PcTK) models the x-ray spectrum of recorded PCD data, with such correlation.<\/p>\n

PcTK output<\/strong><\/p>\n

Users define parameters for PCDs such as the pixel size, the pixel depth, the reference size of electron charges, the electronic noise, etc. PcTK then calculates probabilities of the recorded energy and count at neighboring 3×3 PCD pixels when x-rays are incident onto the center of the pixels (pixel 5 in Fig. 2) and outputs a normalized covariance matrix for 1-keV-width energy windows or a given\u00a0energy windows. It will take minutes or hours, depending on parameters.<\/p>\n

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Fig. 2. An example of electron charge distribution when (a) no fluorescence x-ray is emitted and (b) a fluorescence x-ray is emitted and absorbed by adjacent pixels. Figure is from Ref. 1.<\/figcaption><\/figure>\n
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Fig. 3. Normalized covariance matrices for\u00a01-keV-width energy windows (a) and Nl<\/em>(=4) energy windows (b). Figure is from Ref. 1.<\/figcaption><\/figure>\n

Use cases<\/strong><\/p>\n

From the output of PcTK, users can generate the recorded spectra as shown in Figs. 4\u20136. This process is very fast.<\/p>\n

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Fig. 4. The recorded spectra at each of the 3×3 neighboring pixels when only the central pixel receives x-rays (from Ref. 1)<\/figcaption><\/figure>\n
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Fig. 5 The recorded spectra with different incident energies when all of the pixels receive x-rays (from Ref. 1)<\/figcaption><\/figure>\n
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Fig. 6 The recorded spectra with different PCD parameters (from Ref. 1)<\/figcaption><\/figure>\n

Using the workflow script, users can generate correlated noisy PCD data (Figs. 7f\u20137i) from “material-specific sinograms” (C in Fig. 7)) and other parameters (A\u2013E in Fig. 7).<\/p>\n

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Fig. 7. PCD-CT workflow using PcTK. Figure is from Ref. 1.<\/figcaption><\/figure>\n

There is a caveat. Generating correlated noisy data that are correlated among neighboring pixels, allows for more realistic PCD simulation, but takes longer time (hours). We provide a script that generates uncorrelated<\/em> noisy PCD data with the same expectation. Generating uncorrelated noisy data, where all of PCD data are independent to each other, allows for more efficient computation (minutes) at the expense of the lack of noise correlation. The bottle-neck of the scripts is the way to call a random number generator of Matlab\u2014more specifically, a random number generator is called for each set of 3×3 neighboring PCD pixels. It would be great if users can offer suggestions on more efficient ways or GPU-based programming.<\/p>\n

Ref. 1. Taguchi K, Stierstorfer K, Polster C, Lee O, and Kappler S. Spatio-energetic cross-talk in photon counting detectors: Numerical detector model (PcTK) and workflow for CT image quality assessment. Medical Physics. 2018;45(xx):xxx\u2013xxx. (tentatively accepted). This paper outlines PcTK version 3.2.<\/p>\n

Ref. 2. Taguchi K, Polster C, Lee O, Stierstorfer K, and Kappler S. Spatio-energetic cross-talk in photon counting detectors: Detector model and correlated Poisson data generator. Medical Physics. 2016;43(12):6386\u20136404. DOI:10.1118\/1.4966699<\/a>\u00a0This paper outlines PcTK version 2.1.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

How it works An x-ray photon interacts with photon counting detectors (PCDs) via various phenomena and generates an electron charge cloud or multiple clouds. The clouds may be detected by two or more adjacent PCD pixels and the recorded energy may be lower than the original energy due to charge sharing (Fig. 1b), escape and … <\/p>\n

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